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Produkty / AneuVysion (13, 18, 21, X, Y) 30 testów

AneuVysion (13, 18, 21, X, Y) 30 testów

Nr kat. 32-161075

Producent: ABBOTT / VYSIS

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30 testów.
AneuVysion® (13, 18, 21, X, Y) Multi-color 5 Probe Panel Assay Kit 30 assays IVD/CE Approved. Control slides not included.

The AneuVysion Prenatal Test, which utilizes patented fluorescence in situ hybridization(FISH) technology applied to uncultured amniocytes, provides detection of trisomies 13, 18 and 21 (Down syndrome) and sex chromosome aneusomies in as little as 24 hours. Together these conditions account for nearly two-thirds of all abnormalities identified at the time of amniocentesis, and 85-90% of clinically significant chromosomal abnormalities detected in live-born infants. Review of AneuVysion testing of over 29,000 amniotic fluid samples has found that the test is 99.9% accurate for the detection of trisomies 13, 18, 21, and aneusomies of X and Y.
There are several benefits of the AneuVysion Test. Because the results are rapidly available, within 24 hours after the amniocentesis sample is received in the laboratory (rather than 7-22 days for routine chromosome analysis), patients can benefit psychologically from a shorter time period of uncertainty. A normal AneuVysion result may allow patients a sense of relief in knowing that the majority of chromosome abnormalities for which their fetus was at risk have been ruled out with a very high degree of accuracy. Importantly, in accordance with professional standards6, the availability of AneuVysion results along with consistent clinical information (i.e., fetal anomalies detected by ultrasonography) allows for pregnancy management options that otherwise might not be available due to late gestational age. Finally, in the rare case of a culture failure when standard cytogenetic results cannot be obtained, information on chromosome number for the most likely aneusomies is available.
The AneuVysion Test Kit Includes:
Each AneuVysion kit includes five FISH probes packaged in two probe mixtures, wash reagents, DAP II counterstain and a package insert with detailed protocol information.
Probe Mixture #1
CEP® 18: D18Z1 alpha-satellite DNA probe corresponding to 18p11.1-q11.1 labeled with SpectrumAqua.
CEP X: DXZ1 alpha-satellite DNA probe corresponding to Xp11.1-q11.1 labeled with SpectrumGreenTM
CEP Y: DYZ3 alpha-satellite DNA probe corresponding to Yp11.1-q11.1 labeled with Spectrum Orange
Mixture #1 is complete with labeled probes and non-labeled blocking DNA in hybridization buffer.
Probe Mixture #2
LSI® 13: DNA probe corresponding to the RB1 gene (13q14) labeled with SpectrumGreen.
LSI 21: DNA probe corresponding to loci D21S59, D21S341 and D21S342 (21q22.13-q22.2) labeled with SpectrumOrange.
Mixture # 2 is complete with labeled probes and non-labeled blocking DNA in hybridization buffer.
Strona producenta: www.vysis.com

GENOS, ul. Inowrocławska 9/132, 91-020 Łódź, tel. 42 611 63 11, tel./fax 42 611 63 12, genos@genos.com.pl